lobular breast cancer

GPTKB entity

Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkbp:affects breast tissue
gptkbp:canMetastasizeTo gptkb:meninges
gastrointestinal tract
ovaries
peritoneum
gptkbp:cellType small, uniform cells
gptkbp:commonIn postmenopausal women
gptkbp:diagnosedBy MRI
biopsy
mammography
gptkbp:firstDescribed 1941
gptkbp:frequency accounts for 10-15% of breast cancers
gptkbp:histology single-file cell pattern
https://www.w3.org/2000/01/rdf-schema#label lobular breast cancer
gptkbp:ICD-10_code C50
gptkbp:lessLikelyToExpress gptkb:HER2/neu
gptkbp:lessLikelyToForm palpable mass
gptkbp:lessLikelyToShow microcalcifications on mammogram
gptkbp:marking loss of E-cadherin expression
gptkbp:mayExpress estrogen receptor
progesterone receptor
gptkbp:originatedIn lobules of the breast
gptkbp:prognosis generally similar to ductal breast cancer
gptkbp:riskFactor hormone replacement therapy
family history of breast cancer
increasing age
gptkbp:subspecies gptkb:invasive_lobular_carcinoma
lobular carcinoma in situ
gptkbp:symptom breast swelling
breast thickening
change in breast texture
gptkbp:treatment surgery
radiation therapy
chemotherapy
hormone therapy
targeted therapy
gptkbp:bfsParent gptkb:E-cadherin
gptkbp:bfsLayer 6