Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:binds |
gptkb:beta-catenin
actin filaments |
| gptkbp:component |
adherens junction
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
CTNNA1 gene
CTNNA2 gene CTNNA3 gene |
| gptkbp:foundIn |
animals
humans |
| gptkbp:function |
cell adhesion
|
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-catenin
|
| gptkbp:involvedIn |
tissue morphogenesis
epithelial integrity |
| gptkbp:molecularWeight |
~100 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
cardiomyopathy |
| gptkbp:orthologIn |
gptkb:mouse
gptkb:zebrafish gptkb:Drosophila_melanogaster |
| gptkbp:regulates |
actin cytoskeleton
|
| gptkbp:relatedTo |
cadherin complex
|
| gptkbp:subcellularLocation |
gptkb:cell_membrane
gptkb:cytoplasm |
| gptkbp:UniProtID |
P35221
|
| gptkbp:bfsParent |
gptkb:E-cadherin
|
| gptkbp:bfsLayer |
6
|