Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:uvomorulin
gptkb:cadherin-1 CAM 120/80 |
| gptkbp:associatedWith |
gptkb:hereditary_diffuse_gastric_cancer
gptkb:lobular_breast_cancer |
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodes |
E-cadherin protein
|
| gptkbp:Entrez_Gene_ID |
999
|
| gptkbp:expressedIn |
epithelial tissues
|
| gptkbp:function |
tumor suppression
cell-cell adhesion |
| gptkbp:HGNC_ID |
1748
|
| https://www.w3.org/2000/01/rdf-schema#label |
CDH1 gene
|
| gptkbp:locatedOnChromosome |
16q22.1
|
| gptkbp:lossOfFunctionLeadsTo |
epithelial-mesenchymal transition
|
| gptkbp:mutationAssociatedWith |
germline
increased cancer risk somatic |
| gptkbp:OMIM |
192090
|
| gptkbp:orthologInMouse |
gptkb:Cdh1
|
| gptkbp:product |
gptkb:E-cadherin
|
| gptkbp:proteinFamily |
gptkb:cadherin_superfamily
|
| gptkbp:regulates |
epithelial cell polarity
tissue architecture |
| gptkbp:UniProtID |
P12830
|
| gptkbp:bfsParent |
gptkb:E-cadherin
|
| gptkbp:bfsLayer |
6
|