Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:RNF55
Casitas B-lineage lymphoma proto-oncogene protein |
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:domain |
SH2 domain
RING finger domain |
| gptkbp:encodedBy |
gptkb:CBL_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
gptkb:E3_ubiquitin-protein_ligase
|
| https://www.w3.org/2000/01/rdf-schema#label |
CBL protein
|
| gptkbp:interactsWith |
gptkb:EGFR
gptkb:c-Met gptkb:Src_family_kinases gptkb:Grb2 |
| gptkbp:involvedIn |
signal transduction
|
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:locatedOnChromosome |
11q23.3
|
| gptkbp:molecularWeight |
~120 kDa
|
| gptkbp:mutationAssociatedWith |
leukemia
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:phosphorylates |
tyrosine residues
|
| gptkbp:regulates |
protein degradation
tyrosine kinase signaling receptor internalization |
| gptkbp:UniProtID |
P22681
|
| gptkbp:bfsParent |
gptkb:CBL_gene
|
| gptkbp:bfsLayer |
7
|