Statements (64)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:Oncology
ovarian cancer |
| gptkbp:composed_of |
gptkb:BRCA1_protein
RAP80 protein |
| gptkbp:has_role |
cell cycle regulation
|
| https://www.w3.org/2000/01/rdf-schema#label |
BRCA1-RAP80 complex
|
| gptkbp:interacts_with |
gptkb:CHK2
gptkb:H2_AX gptkb:ATM_protein gptkb:BRCA2 gptkb:FANCD2 gptkb:MRE11 gptkb:RAD51 p53 protein NBS1 FANCI ubiquitin |
| gptkbp:involved_in |
DNA damage response
DNA repair apoptosis cellular homeostasis cellular metabolism cellular stress response chromatin remodeling immune response signal transduction cellular proliferation cellular response to stress cellular senescence chromosomal stability tumor suppression cellular aging cellular differentiation genomic stability cellular signaling pathways nucleotide excision repair transcriptional regulation cellular repair mechanisms telomere maintenance cellular differentiation pathways cellular homeostatic mechanisms cellular repair pathways cellular growth regulation cellular metabolic pathways cellular repair processes cellular apoptosis cellular defense mechanisms double-strand break repair cellular regulatory mechanisms base excision repair mismatch repair protein ubiquitination repair of interstrand cross-links cellular repair activities cellular repair functions cellular maintenance functions cellular signaling mechanisms |
| gptkbp:localization |
gptkb:Atom
|
| gptkbp:regulates |
DNA replication
gene expression homologous recombination |
| gptkbp:bfsParent |
gptkb:BRCA1
|
| gptkbp:bfsLayer |
6
|