Oncology

GPTKB entity

Statements (969)

Predicate	Object
gptkbp:instance_of	gptkb:disease gptkb:virus gptkb:astrology gptkb:Oncology gptkb:sunglasses gptkb:Neoplatonism gptkb:healthcare_professionals gptkb:constellation
gptkbp:advocacy	gptkb:Retinoblastoma_International gptkb:The_Children's_Eye_Foundation gptkb:Leukemia_&_Lymphoma_Society gptkb:National_Institutes_of_Health gptkb:The_American_Academy_of_Pediatrics gptkb:The_American_Cancer_Society gptkb:Children's_Oncology_Group
gptkbp:affects	gptkb:Brain gptkb:Skin gptkb:Cell cell growth cats stomach plasma cells T-cells retina lymphatic system blood cells chronic health issues increased susceptibility to other diseases reduced lifespan
gptkbp:age_group	45-70 years
gptkbp:aims_to	Improve patient outcomes
gptkbp:apparent_magnitude	3.5 3.9 4.2 4.3 4.5 4.0 4.4 4.6
gptkbp:associated_gem	gptkb:Chaos
gptkbp:associated_metal	gptkb:Platinum gptkb:silver
gptkbp:associated_with	gptkb:HIV gptkb:Oncology gptkb:Philadelphia_chromosome gptkb:Klinefelter_syndrome gptkb:HTLV-1_virus gptkb:neurofibromatosis gptkb:HIV/_AIDS gptkb:Down_syndrome autoimmune diseases skin lesions chronic inflammation lymphadenopathy HIV infection helicobacter pylori infection hepatosplenomegaly EBV infection other cancers cytopenias ALK gene rearrangement B symptoms Nodal involvement elevated lactate dehydrogenase extranodal involvement CD30 positivity
gptkbp:atmosphere	gptkb:Beehive_Cluster gptkb:NGC_2535 gptkb:NGC_2623
gptkbp:can_be_indolent	gptkb:true
gptkbp:can_be_used_to	gptkb:patches tumors plaques spinal compression lytic bone lesions soft tissue masses Bence Jones protein in urine M protein in serum pathologic fractures plasma cell infiltration
gptkbp:can_cause	gptkb:anemia fatigue weight loss pain emotional distress kidney damage changes in appetite hypercalcemia disfigurement bone lesions
gptkbp:can_detect	gptkb:MRI gptkb:medical_imaging CT scan blood tests PET scan immunofixation electrophoresis serum protein electrophoresis
gptkbp:can_involve	gptkb:blood Minimally invasive techniques Robotic surgery lymph nodes
gptkbp:can_lead_to	gptkb:death disability secondary infections financial burden immune system dysfunction metastasis organ failure secondary cancers hypercalcemia organ dysfunction vision loss myeloma eye removal compromised immune system infection complications lymphoma in lymph nodes
gptkbp:can_metastasize_to	gptkb:Skeleton gptkb:Brain lymph nodes
gptkbp:can_recur_after	treatment
gptkbp:can_relapse	gptkb:true
gptkbp:can_result_in	renal impairment
gptkbp:cause	obesity radiation exposure genetic mutations tobacco use certain infections feline leukemia exposure to carcinogens abnormal proliferation of B-cells
gptkbp:cause_of_death	many countries
gptkbp:caused_by	environmental factors genetic mutations exposure to chemicals mutations in the RB1 gene
gptkbp:cell_target	gptkb:B_lymphocytes T lymphocytes bone marrow cells
gptkbp:characterized_by	abnormal proliferation of plasma cells
gptkbp:clinical_trial	gptkb:immunotherapy ongoing targeted therapies ongoing research new treatment options new therapies necrosis studies on combination therapies ongoing research for new therapies immunotherapy studies targeted therapy studies infiltrative growth microvascular proliferation mitotic activity immunotherapy approaches being explored investigating targeted therapies CAR T-cell therapy trials ongoing
gptkbp:collaborates_with	gptkb:Medical_Oncologists Radiation Oncologists
gptkbp:color	gptkb:White gptkb:silver
gptkbp:common_age_of_diagnosis	under 5 years old
gptkbp:common_imaging_finding	mass effect midline shift ring-enhancing lesions
gptkbp:common_subtype	gptkb:primary_glioblastoma gptkb:secondary_glioblastoma
gptkbp:common_symptom	vision problems weakness balance issues personality changes speech difficulties
gptkbp:community_health	not a zoonotic disease
gptkbp:community_impact	affects thousands annually incidence rates vary by region
gptkbp:compatibility	gptkb:Scorpio gptkb:Taurus gptkb:Virgo gptkb:Pisces
gptkbp:complication	gptkb:disease gptkb:anemia bleeding
gptkbp:condition	gptkb:Figaro gptkb:anemia malnutrition edema neurocognitive decline
gptkbp:conducts_research_on	cancer treatment advancements genetic factors in cancer immunotherapy effectiveness
gptkbp:contains	the Beehive Cluster (M44) the star Acubens the star Asellus Australis the star Asellus Borealis the star Tegmine
gptkbp:contains_star	gptkb:Acubens gptkb:Asellus_Australis gptkb:Asellus_Borealis gptkb:Beta_Cancri gptkb:Delta_Cancri gptkb:Gamma_Cancri Beta Cancri (Altarf) Tarf
gptkbp:coordinates	+90° to -60°
gptkbp:date	June 21 -July 22
gptkbp:deals_with	Solid tumors
gptkbp:death	varies by stage improving over time depends on stage lower in adults higher in children higher in early stages around 70% for advanced cases over 95% for localized cases 5% at 5 years
gptkbp:demographics	more common in males more common in older adults
gptkbp:diagnosis	gptkb:MRI gptkb:Oncology gptkb:ELISA gptkb:lipoma PCR CT scan variable blood tests imaging studies blood test clinical evaluation varies by age biopsy endoscopy poor imaging tests eye examination bone marrow biopsy PET scan benign tumors varies by subtype depends on stage at diagnosis skin biopsy variable prognosis other sarcomas varies by response to treatment varies by genetic factors dermatopathologists other non-Hodgkin lymphomas reactive lymphadenopathy
gptkbp:discovered_by	gptkb:1964
gptkbp:diseases	gptkb:Oncology gptkb:Feline_immunodeficiency_virus gptkb:Murine_leukemia_virus gptkb:Simian_leukemia_virus secondary infections immunosuppression
gptkbp:divisions	gptkb:Number_7 Number 2
gptkbp:duration	varies
gptkbp:element	gptkb:Water gptkb:water
gptkbp:epidemiology	more common in men incidence increases with age prevalence varies by region rare compared to B-cell lymphomas
gptkbp:events	psychosocial support regular check-ups clinical evaluations monitoring for recurrence monitoring for relapse regular imaging management of side effects psychosocial support recommended supportive care services available
gptkbp:exhibits	pleural effusion pericardial effusion central nervous system involvement
gptkbp:family	gptkb:Retroviridae
gptkbp:famous_person	gptkb:Selena_Marie_Gomez gptkb:Meryl_Streep gptkb:Robin_Williams gptkb:Harry_Potter gptkb:Tom_Hanks gptkb:Winnie_the_Pooh gptkb:Princess_Diana gptkb:Peter_Pan gptkb:Dory Marilyn Munroe
gptkbp:financial_support	gptkb:educational_resources counseling counseling services support groups
gptkbp:first_described_by	gptkb:1980s 1930s in the 19th century Hugh A. Mc Allister
gptkbp:flora	gptkb:Lily gptkb:White_Rose
gptkbp:focuses_on	gptkb:cancer_treatment Surgical treatment of cancer Cancers of the female reproductive system
gptkbp:genetic_predisposition	gptkb:familial_retinoblastoma gptkb:sporadic_retinoblastoma
gptkbp:genetic_studies	gptkb:NOTCH1 gptkb:EGFR gptkb:Genetics gptkb:TP53_mutation gptkb:PTEN gptkb:TP53 RHOA mutation CDH1 mutation FBXW7 CDKN2 A deletion
gptkbp:genus	gptkb:Gammaretrovirus
gptkbp:geographic_distribution	worldwide higher incidence in East Asia lower incidence in North America
gptkbp:grades	IV
gptkbp:grooming_needs	can vary
gptkbp:has_achieved	gptkb:disease gptkb:anemia neurological symptoms infections thrombosis fractures neuropathy cardiac issues secondary malignancies tumor lysis syndrome
gptkbp:has_area	506 square degrees
gptkbp:has_field	gptkb:Oncology Radiation Oncology Pediatric Oncology Neuro-Oncology Hematology-Oncology Geriatric Oncology
gptkbp:has_historical_significance	recognized by ancient civilizations
gptkbp:has_research_areas	clinical trials oncology pharmacology genomics epidemiology
gptkbp:has_research_focus	gptkb:Brain_Tumor_Foundation gptkb:National_Brain_Tumor_Society gptkb:American_Brain_Tumor_Association Tumor Biology Treatment Outcomes Patient Quality of Life Innovative Therapies Risk Factors Survivorship Issues Screening Methods
gptkbp:has_type	gptkb:large_cell_lymphoma,_unclassifiable gptkb:primary_mediastinal_large_B-cell_lymphoma gptkb:Oncology gptkb:T-cell_prolymphocytic_leukemia gptkb:Burkitt_lymphoma transitional cell carcinoma follicular lymphoma diffuse large B-cell lymphoma mantle cell lymphoma
gptkbp:has_weakness	Moody Sensitive Pessimistic Suspicious Clingy
gptkbp:historical_context	first described in 1980s
gptkbp:homeworld	gptkb:Moon
https://www.w3.org/2000/01/rdf-schema#label	Oncology
gptkbp:impact	cat population
gptkbp:includes	gptkb:hospice_care gptkb:Ovarian_Cancer Supportive Care Cervical Cancer Lymph node dissection Palliative surgery Tumor resection Uterine Cancer Vaginal Cancer Vulvar Cancer
gptkbp:involves	gptkb:immunotherapy gptkb:surgery Chemotherapy Radiation Therapy Targeted Therapy Hormonal Therapy
gptkbp:is_a	gptkb:Oncology malignant neoplasm type of cancer Blood cancer
gptkbp:is_a_symbol_of	the crab
gptkbp:is_adjacent_to	gptkb:Canis_Minor gptkb:Hydra gptkb:Virgo gptkb:Gemini gptkb:Leo
gptkbp:is_associated_with	gptkb:Clinical_Trials gptkb:HIV/_AIDS Research Institutions Clinical trials Pharmaceutical Companies environmental factors Clinical Guidelines autoimmune diseases chronic diseases inflammation lifestyle choices the color blue family history Genetic Testing emotional depth genetic mutations immune system dysfunction Pap Smear epigenetic changes chronic inflammation viral infections immunosuppressive therapy the element of water family and home the color white the summer solstice chromosomal translocations the color gray the color silver the month of July HPV Vaccination nurturing qualities intuitive nature the astrological sign of Cancer B symptoms the astrological element of water the astrological quality of cardinal the element of water in astrology the planet Moon in astrology the astrological sign for those born between June 21 and July 22 the fourth house in astrology the gemstone emerald the gemstone moonstone the gemstone pearl the gemstone ruby the planet Moon
gptkbp:is_challenged_by	Resource allocation Access to care Ethical considerations Patient comorbidities Tumor recurrence
gptkbp:is_characterized_by	skin lesions abnormal cell growth lymphadenopathy hepatomegaly splenomegaly uncontrolled cell growth high proliferation rate systemic symptoms invasion of surrounding tissues monoclonal plasma cell proliferation abnormal cell division potential to metastasize B symptoms immunophenotypic features presence of large atypical lymphoid cells rapid growth of lymphoid tissue abnormal T-cells clonal proliferation
gptkbp:is_common_in	gptkb:women gptkb:African_Americans gptkb:children young adults adults elderly men smokers females older adults males individuals over 65 people with a family history of cancer
gptkbp:is_connected_to	the concept of home and family in astrology the lunar cycle in astrology
gptkbp:is_considered	a type of cancer
gptkbp:is_discussed_in	oncology conferences
gptkbp:is_documented_in	gptkb:literature
gptkbp:is_effective_against	gptkb:true
gptkbp:is_essential_for	Cancer staging Tumor board discussions
gptkbp:is_evaluated_by	Patient Satisfaction Surveys Radiologists Quality Assurance Programs Survival Rates Pathologists Outcomes Research Oncology nurses Complication Rates
gptkbp:is_funded_by	government grants pharmaceutical companies private donations
gptkbp:is_global_health_issue	gptkb:true
gptkbp:is_home_to	several deep-sky objects the open cluster NGC 2158 the planetary nebula NGC 2626 the star cluster M44 (the Beehive) the star cluster NGC 2419
gptkbp:is_influenced_by	gptkb:activists Research Funding Healthcare Policies environmental factors Clinical Guidelines circadian rhythms genetic factors Advancements in technology Advancements in Medical Technology
gptkbp:is_informed_by	gptkb:activists gptkb:Genetics gptkb:Radiology Clinical Research Evidence-Based Medicine Health Economics Molecular Biology Pathology Pharmacology Genetic testing Patient history Treatment Protocols Patient Care Standards Ethics in Medicine Quality of Life Research Survivorship Research Biomarker research Tumor characteristics
gptkbp:is_involved_in	gptkb:Gastric_Cancer_Foundation gptkb:National_Institutes_of_Health gptkb:Cancer_Research_UK Public Awareness Campaigns Patient Education Support Groups Advocacy Efforts Multidisciplinary Care Teams
gptkbp:is_known_for	its faint stars compared to other constellations
gptkbp:is_linked_to	Quality of life Patient satisfaction environmental factors lifestyle choices Survival rates
gptkbp:is_located_in	the northern celestial hemisphere thigh abdomen retroperitoneum
gptkbp:is_managed_by	oncologists radiation oncologists hematologists
gptkbp:is_monitored_by	blood tests imaging studies clinical assessments regular check-ups follow-up appointments follow-up imaging regular blood tests bone marrow tests
gptkbp:is_notable_for	the presence of the M67 star cluster
gptkbp:is_often_seen_in	gptkb:Oncology gptkb:Kaposi's_sarcoma gptkb:children adults elderly benign tumors non-cancerous conditions
gptkbp:is_one_of	the 88 modern constellations the 48 constellations listed by Ptolemy
gptkbp:is_part_of	gptkb:health_services gptkb:Oncology gptkb:non-Hodgkin_lymphoma gptkb:the_Milky_Way_galaxy public health clinical trials patient care medical education the zodiac Obstetrics and Gynecology the celestial sphere the ecliptic plane the Hercules constellation family Multidisciplinary cancer care plasma cell disorders lymphatic system hematologic malignancies neoplastic diseases cancer spectrum
gptkbp:is_practiced_in	Hospitals Outpatient Clinics Cancer Centers Gynecologic Oncologists
gptkbp:is_promoted_by	Conferences Professional societies Public awareness campaigns
gptkbp:is_recognized_by	gptkb:the_World_Health_Organization gptkb:World_Health_Organization gptkb:National_Institutes_of_Health gptkb:American_Board_of_Obstetrics_and_Gynecology gptkb:Society_of_Gynecologic_Oncology Accreditation bodies Medical associations eczema psoriasis the International Astronomical Union
gptkbp:is_regulated_by	Health Authorities Health authorities Medical boards Medical Boards
gptkbp:is_related_to	gptkb:myelodysplastic_syndromes gptkb:Oncology gptkb:smoldering_multiple_myeloma environmental factors clinical trials Women's Health genetic mutations viral infections Waldenström macroglobulinemia staging systems tumor markers plasma cell dyscrasias light chain amyloidosis
gptkbp:is_represented_in	the crab the symbol ♋
gptkbp:is_studied_for	preventive measures
gptkbp:is_studied_in	gptkb:medical_research public health clinical trials oncology pathology biomedical science
gptkbp:is_supported_by	gptkb:National_Institutes_of_Health Research organizations Funding agencies Pharmaceutical companies
gptkbp:is_taught_in	Medical schools Fellowship Programs Residency programs Fellowship programs Medical Schools Residency Programs
gptkbp:is_used_in	gptkb:astrology gptkb:navigation star gazing navigational astronomy
gptkbp:is_visible_from	gptkb:Earth January to June the spring months
gptkbp:is_vulnerable_to	kittens inactivated reduces risk of infection high-risk adult cats recombinant
gptkbp:issues	Diagnosis of gynecologic cancers Prevention of gynecologic cancers Treatment of gynecologic cancers
gptkbp:jewels	gptkb:Chaos gptkb:Ruby
gptkbp:median_survival	15 months
gptkbp:mythology	Associated with the Moon Goddess Associated with the Moon Linked to the myth of Hercules associated with the myth of Hercules
gptkbp:named_after	gptkb:the_crab_in_Greek_mythology the Latin word for crab
gptkbp:notable_case	notable individuals
gptkbp:notable_quote	" Family is everything." " Home is where the heart is." " Emotions are my strength." " I am my own worst critic." " I feel deeply." " I need to feel secure."
gptkbp:number_of_stages	stage I stage IV stage II stage III
gptkbp:occurs_in	gptkb:Skeleton gptkb:Skin gptkb:children rare adults lungs 1 in 15,000 births colon breast prostate soft tissue increasing in some populations 3.19 per 100,000 people
gptkbp:origin	astrocytes
gptkbp:originated_in	gptkb:MDM2 gptkb:TP53 Personalized medicine CDK4 adipose tissue T-cells lymphatic system Innovative therapies New surgical techniques
gptkbp:owner	important for prevention symptoms to watch for testing recommendations
gptkbp:personal_life	obesity lack of physical activity diet high in salted foods
gptkbp:personality_trait	gptkb:Intuitive Protective Nurturing Caring Creative Sensitive Sympathetic Home-loving
gptkbp:premiered_on	adolescents ages 2 to 5
gptkbp:prevalence	rare varies by region more common in children rare overall rare in adults
gptkbp:prevention	regular exercise vaccination healthy diet sun protection early detection limiting alcohol consumption avoiding tobacco treatment of infections regular medical check-ups protecting skin from UV radiation management of autoimmune diseases vaccination against certain viruses
gptkbp:product_quality	gptkb:Cardinal
gptkbp:provides_guidance_on	ASCO guidelines NCCN guidelines EANO guidelines
gptkbp:public_awareness	gptkb:Retinoblastoma_Awareness_Month September Lymphoma Awareness Month sarcoma awareness month
gptkbp:rarity	gptkb:children
gptkbp:related_species	gptkb:seafood
gptkbp:requires	Continuing Education Specialized Training Specialized training Board Certification Treatment Planning Patient Assessment Postoperative care Preoperative assessment radiation therapy multidisciplinary approach monitoring for recurrence long-term follow-up Diagnosis of Cancer
gptkbp:research	ongoing targeted therapies new genetic markers improved imaging techniques biomarkers for prognosis immunotherapy options
gptkbp:research_focus	gptkb:gene_therapy gptkb:immunotherapy quality of life biomarkers genetic factors genetic mutations early detection targeted therapy new treatment options vaccine development new therapies diagnostic methods treatment options improving treatment outcomes treatment resistance early detection methods pathogenesis genetic profiling biomarkers for diagnosis understanding genetic predisposition
gptkbp:risk_factor	age genetic disorders autoimmune diseases obesity radiation exposure family history genetic mutations smoking gender Helicobacter pylori infection viral infections weakened immune system certain chemicals chronic gastritis HIV infection exposure to radiation previous radiation exposure genetic syndromes immune system disorders exposure to certain chemicals outdoor cats previous cancer treatment multi-cat households immunocompromised cats family history of lymphoma
gptkbp:scientific_classification	gptkb:aggressive_lymphoma gptkb:Oncology gptkb:non-Hodgkin_lymphoma localized systemic hematologic malignancy solid tumor
gptkbp:screenings	not routinely screened high-risk children high-risk individuals may be screened
gptkbp:side_effect	gptkb:anemia fatigue nausea increased risk of infections hair loss increased risk of infection mouth sores
gptkbp:strength	gptkb:Loyal gptkb:Intuitive gptkb:Loyalty Emotional Empathy Intuition Tenacity Emotionally intelligent
gptkbp:symbol	gptkb:seafood gptkb:The_Crab
gptkbp:symptoms	gptkb:anemia fatigue headache nausea weight loss abdominal pain fever limited mobility nutritional support pain pain relief swelling vomiting seizures supportive care vision problems discomfort night sweats persistent cough swollen lymph nodes skin lesions itching bone pain easy bruising lethargy skin changes cognitive dysfunction lump unexplained weight loss hydration therapy crossed eyes frequent infections antipyretics increased infections white pupil
gptkbp:transmission	gptkb:blood breast milk saliva urine
gptkbp:treatment	gptkb:Medicine gptkb:immunotherapy gptkb:Oncology gptkb:CAR_T-cell_therapy gptkb:tumor-treating_fields gptkb:surgery varies hospitals variable clinical trials research institutions nurses nutritional support side effects survival rate supportive care monoclonal antibodies radiation therapy varies by individual chemotherapy oncologists psychosocial support targeted therapy tumor heterogeneity corticosteroids dermatologists access to care pharmacists recurrence surgeons laser therapy symptom management relapse oncology clinics drug resistance progression topical steroids remission stem cell transplant vitrectomy long-term follow-up care phototherapy depends on subtype systemic therapy depends on stage at diagnosis progression-free survival radiation therapists antibiotics for secondary infections cryotherapy blood-brain barrier hematologist biologic therapy depends on response to therapy monitoring for late effects depends on overall health of patient good in early stages poor in advanced stages
gptkbp:type	gptkb:Oncology gptkb:Kaposi's_sarcoma gptkb:extramedullary_plasmacytoma gptkb:solitary_plasmacytoma bilateral unilateral retrovirus malignant neoplasm
gptkbp:type_of	gptkb:Sézary_syndrome gptkb:angioimmunoblastic_T-cell_lymphoma gptkb:mycosis_fungoides gptkb:peripheral_T-cell_lymphoma_not_otherwise_specified gptkb:Oncology gptkb:systemic_ALCL gptkb:B-cell_ALL gptkb:T-cell_ALL gptkb:Fe_LV-C gptkb:dedifferentiated_liposarcoma gptkb:myxoid_liposarcoma gptkb:pleomorphic_liposarcoma well-differentiated liposarcoma primary cutaneous ALCL Fe LV-A Fe LV-B
gptkbp:type_of_care	growth factors antibiotics blood transfusions
gptkbp:utilizes	gptkb:Clinical_Trials Imaging techniques
gptkbp:works_with	gptkb:Oncology Radiation Oncologists Surgical Oncologists
gptkbp:bfsParent	gptkb:Henry_Nixon gptkb:Olivia_Newton-John gptkb:National_Institutes_of_Health gptkb:Nelson_Mandela gptkb:Nina_Simone gptkb:Jimmy_Carter gptkb:The_George_Washington_University_Hospital gptkb:Biology gptkb:The_Med_Star_Washington_Hospital_Center
gptkbp:bfsLayer	3