Properties (62)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein
|
| gptkbp:associatedWith |
Ataxia-telangiectasia
|
| gptkbp:diedIn |
cellular senescence
|
| gptkbp:established |
p53
|
| gptkbp:function |
DNA damage response
|
| gptkbp:geneticDiversity |
gptkb:ATM
Ataxia-telangiectasia syndrome |
| https://www.w3.org/2000/01/rdf-schema#label |
ATM protein
|
| gptkbp:interactsWith |
MRE11
NBS1 |
| gptkbp:involvedIn |
double-strand break repair
|
| gptkbp:isActiveIn |
cell cycle progression
|
| gptkbp:isAssociatedWith |
metabolic processes
cellular aging cancer progression neurodegeneration cellular signaling dysregulation |
| gptkbp:isCriticizedFor |
cellular homeostasis
cellular function DNA integrity cellular repair pathways |
| gptkbp:isEngagedIn |
certain cancer therapies
|
| gptkbp:isEquippedWith |
proper cell cycle regulation
|
| gptkbp:isExaminedBy |
gptkb:ATM_gene
|
| gptkbp:isInvolvedIn |
apoptosis
cellular stress response chromatin remodeling immune response DNA repair mechanisms cellular proliferation chromosomal stability tumor suppression cellular differentiation cellular signaling pathways cellular repair mechanisms cellular response to DNA damage cellular repair processes cellular apoptosis pathways cellular homeostasis maintenance cellular repair signaling |
| gptkbp:isLinkedTo |
genetic disorders
tumorigenesis cellular dysfunction cancer predisposition genetic instability radiation sensitivity |
| gptkbp:isLocatedIn |
development
various tissues |
| gptkbp:isPartOf |
signal transduction pathways
cellular machinery protein complexes DNA damage response network DNA damage signaling pathway |
| gptkbp:isRegulatedBy |
cellular signaling molecules
|
| gptkbp:isStudiedIn |
cancer research
|
| gptkbp:isTrainedIn |
cancer treatment
|
| gptkbp:isUtilizedFor |
genomic stability
|
| gptkbp:isVisitedBy |
DNA double-strand breaks
|
| gptkbp:location |
nucleus
|
| gptkbp:regulates |
cellular response to stress
|
| gptkbp:regulatoryBody |
H2AX
|
| gptkbp:type |
serine/threonine kinase
|