Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:CASNumber |
1265912-17-2
|
| gptkbp:hasApplication |
biological research
cell signaling studies |
| gptkbp:hasMolecularFormula |
C21H18N4O3S
|
| https://www.w3.org/2000/01/rdf-schema#label |
BIX02189
|
| gptkbp:inhibitedBy |
gptkb:GSK-3
gptkb:GSK-3α gptkb:GSK-3β |
| gptkbp:is_not_selective_for |
gptkb:MEK1
gptkb:MEK2 gptkb:MEK3 gptkb:MEK6 gptkb:MEK7 gptkb:MEK4 |
| gptkbp:is_selective_inhibitor_of |
gptkb:MEK5
|
| gptkbp:IUPACName |
N-(6-(3-morpholin-4-ylpropoxy)pyridin-3-yl)-4-(pyridin-3-ylmethyl)thiazol-2-amine
|
| gptkbp:meltingPoint |
not widely reported
|
| gptkbp:molecularWeight |
406.46 g/mol
|
| gptkbp:PubChem_CID |
46224516
CHEMBL2039155 |
| gptkbp:used_in |
cancer research
neurobiology research ERK5 pathway inhibition MAPK pathway studies |
| gptkbp:bfsParent |
gptkb:ERK5_pathway
|
| gptkbp:bfsLayer |
7
|