Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:leukemia
gptkb:chronic_myeloid_leukemia |
| gptkbp:cause |
uncontrolled cell proliferation
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
BCR-ABL gene fusion
|
| gptkbp:hasBiologicalActivity |
tyrosine kinase activity
|
| gptkbp:hasComponent |
gptkb:BCR_protein
ABL tyrosine kinase |
| gptkbp:resultedIn |
Philadelphia chromosome translocation
|
| gptkbp:target |
gptkb:bosutinib
gptkb:dasatinib gptkb:ponatinib gptkb:imatinib gptkb:nilotinib |
| gptkbp:bfsParent |
gptkb:ABL1_gene
gptkb:p190_BCR-ABL gptkb:c-Abl |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
BCR-ABL fusion protein
|