Statements (19)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
gptkb:chronic_myeloid_leukemia
leukemia |
gptkbp:cause |
uncontrolled cell proliferation
|
gptkbp:discoveredIn |
1980s
|
gptkbp:encodedBy |
BCR-ABL gene fusion
|
gptkbp:hasBiologicalActivity |
tyrosine kinase activity
|
gptkbp:hasComponent |
gptkb:BCR_protein
ABL tyrosine kinase |
https://www.w3.org/2000/01/rdf-schema#label |
BCR-ABL fusion protein
|
gptkbp:resultedIn |
Philadelphia chromosome translocation
|
gptkbp:target |
gptkb:bosutinib
gptkb:dasatinib gptkb:ponatinib gptkb:imatinib gptkb:nilotinib |
gptkbp:bfsParent |
gptkb:ABL1_gene
gptkb:p190_BCR-ABL |
gptkbp:bfsLayer |
7
|