Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
Breakpoint cluster region protein
|
| gptkbp:associatedWith |
gptkb:chronic_myelogenous_leukemia
|
| gptkbp:domain |
gptkb:PH_domain
gptkb:RhoGEF_domain C2 domain |
| gptkbp:encodedBy |
BCR gene
|
| gptkbp:formsFusionGeneWith |
ABL1 protein
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
serine/threonine-protein kinase activity
GTPase-activating protein activity |
| gptkbp:fusionProtein |
gptkb:BCR-ABL
|
| gptkbp:involvedIn |
cell differentiation
cell proliferation signal transduction |
| gptkbp:location |
chromosome 22
|
| gptkbp:molecularWeight |
160 kDa
|
| gptkbp:phosphorylates |
serine 354
tyrosine 177 |
| gptkbp:UniProtID |
gptkb:P11274
|
| gptkbp:bfsParent |
gptkb:BCR
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
BCR protein
|