Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
BCL-X(L)
BCL2-like 1 isoform 1 BCL2L1-001 |
| gptkbp:alternativeSplicing |
BCL-XS
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
gptkb:BCL2L1_gene
|
| gptkbp:Entrez_Gene_ID |
598
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
inhibits apoptosis
|
| https://www.w3.org/2000/01/rdf-schema#label |
BCL-XL
|
| gptkbp:inhibitedBy |
cytochrome c release
|
| gptkbp:interactsWith |
gptkb:BAD
gptkb:BID gptkb:BAX gptkb:BAK |
| gptkbp:locatedOnChromosome |
gptkb:20q11.21
|
| gptkbp:location |
mitochondrial outer membrane
|
| gptkbp:memberOf |
gptkb:Bcl-2_protein_family
|
| gptkbp:molecularWeight |
~30 kDa
|
| gptkbp:orthologInMouse |
Bcl2l1
|
| gptkbp:PDB |
gptkb:1R2D
|
| gptkbp:prevention |
caspase activation
|
| gptkbp:regulates |
cell death
|
| gptkbp:structure |
contains BH1, BH2, BH3, BH4 domains
|
| gptkbp:target |
A-1331852
navitoclax |
| gptkbp:UniProtID |
gptkb:Q07817
|
| gptkbp:upregulatedBy |
some cancers
|
| gptkbp:bfsParent |
gptkb:BAX
|
| gptkbp:bfsLayer |
6
|