BCL2-associated X protein

URI: https://gptkb.org/entity/BCL2-associated_X_protein
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:BAX
gptkbp:discoveredIn 1993
gptkbp:encodedBy BAX gene
gptkbp:Entrez_Gene_ID 581
gptkbp:expressedIn various tissues
gptkbp:form heterodimers
homodimers
gptkbp:function promotes apoptosis
https://www.w3.org/2000/01/rdf-schema#label BCL2-associated X protein
gptkbp:inhibitedBy gptkb:BCL2
gptkbp:interactsWith gptkb:BCL-XL
gptkb:BAK
gptkb:BCL2
gptkbp:locatedIn mitochondrion
gptkbp:locatedOnChromosome gptkb:19q13.3
gptkbp:memberOf gptkb:Bcl-2_protein_family
gptkbp:molecularWeight 21 kDa
gptkbp:OMIM 600040
gptkbp:PDB gptkb:1F16
gptkbp:regulates cell death
gptkbp:role cytochrome c release
mitochondrial outer membrane permeabilization
intrinsic apoptotic pathway
gptkbp:significance implicated in cancer
implicated in neurodegenerative diseases
gptkbp:species gptkb:Homo_sapiens
gptkbp:structure contains BH1 domain
contains BH2 domain
contains BH3 domain
gptkbp:UniProtID gptkb:Q07812
gptkbp:bfsParent gptkb:BAX
gptkbp:bfsLayer 6