Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:NTRK1
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:congenital_insensitivity_to_pain_with_anhidrosis |
| gptkbp:binds |
gptkb:nerve_growth_factor_(NGF)
|
| gptkbp:discoveredIn |
1986
|
| gptkbp:encodedBy |
gptkb:NTRK1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
gptkb:receptor_tyrosine_kinase
|
| https://www.w3.org/2000/01/rdf-schema#label |
trk-A
|
| gptkbp:involvedIn |
signal transduction
neuronal differentiation neuronal survival |
| gptkbp:locatedOnChromosome |
1q23.1
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:memberOf |
neurotrophic tyrosine receptor kinase family
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:phosphorylates |
autophosphorylation upon ligand binding
|
| gptkbp:structure |
transmembrane domain
extracellular ligand-binding domain intracellular tyrosine kinase domain |
| gptkbp:UniProtID |
gptkb:P04629
|
| gptkbp:bfsParent |
gptkb:HGNC:8007
|
| gptkbp:bfsLayer |
7
|