Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
chromosomal band
|
| gptkbp:alsoKnownAs |
gptkb:Philadelphia_chromosome
|
| gptkbp:associatedWith |
gptkb:chronic_myeloid_leukemia
leukemia |
| gptkbp:chromosomesInvolved |
gptkb:chromosome_9
chromosome 22 |
| gptkbp:consequence |
constitutive tyrosine kinase activity
|
| gptkbp:cytogeneticNotation |
t(9;22)(q34;q11)
|
| gptkbp:discoveredBy |
David Hungerford
Peter Nowell |
| gptkbp:discoveredIn |
1960
|
| gptkbp:formsFusionGeneWith |
gptkb:ABL1
gptkb:BCR |
| gptkbp:hasDiagnosticMethod |
gptkb:FISH
PCR karyotyping |
| https://www.w3.org/2000/01/rdf-schema#label |
t(9;22) translocation
|
| gptkbp:locationOnChromosome22 |
q11
|
| gptkbp:locationOnChromosome9 |
q34
|
| gptkbp:result |
gptkb:BCR-ABL_fusion_gene
|
| gptkbp:targetedTherapy |
gptkb:dasatinib
gptkb:imatinib gptkb:nilotinib |
| gptkbp:bfsParent |
gptkb:chromosome_9q34
gptkb:acute_lymphoblastic_leukemia_(ALL) |
| gptkbp:bfsLayer |
7
|