|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Philadelphia_chromosome-positive_leukemia
gptkb:chronic_myeloid_leukemia
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:domain
|
gptkb:PH_domain
gptkb:RhoGEF_domain
C2 domain
serine/threonine kinase domain
coiled-coil domain
|
|
gptkbp:encodes
|
gptkb:BCR_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000186716
613
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:formsFusionGeneWith
|
gptkb:ABL1
|
|
gptkbp:fullName
|
gptkb:Breakpoint_Cluster_Region
|
|
gptkbp:function
|
serine/threonine kinase activity
GTPase-activating protein activity
|
|
gptkbp:fusionGeneName
|
gptkb:BCR-ABL
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:1014
|
|
gptkbp:involvedIn
|
cell differentiation
cell proliferation
signal transduction
|
|
gptkbp:length
|
1271 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 22
|
|
gptkbp:molecularWeight
|
142 kDa
|
|
gptkbp:mutationAssociatedWith
|
oncogenic transformation
|
|
gptkbp:OMIM
|
151410
|
|
gptkbp:orthologInMouse
|
gptkb:Bcr
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P11274
|
|
gptkbp:bfsParent
|
gptkb:RAPGEF1
gptkb:BC_Rail
gptkb:C._R._Bard
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BCR
|