retinoblastoma protein pathway
GPTKB entity
Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:activatedBy |
hypophosphorylation of RB protein
|
| gptkbp:decommissioned |
hyperphosphorylation of RB protein
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:dysfunctionLeadsTo |
gptkb:cancer
|
| https://www.w3.org/2000/01/rdf-schema#label |
retinoblastoma protein pathway
|
| gptkbp:inhibitedBy |
E2F activity
|
| gptkbp:involvedIn |
gptkb:RB1
|
| gptkbp:involvesModification |
phosphorylation
|
| gptkbp:involvesProtein |
gptkb:cyclin_D
gptkb:CDK4 gptkb:CDK6 gptkb:E2F_transcription_factors gptkb:retinoblastoma_protein |
| gptkbp:processor |
gptkb:G1/S_transition
|
| gptkbp:regulates |
cell cycle
|
| gptkbp:bfsParent |
gptkb:E2F1_gene
|
| gptkbp:bfsLayer |
8
|