Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
gptkb:retinoblastoma_protein_pathway
gptkb:cancer |
| gptkbp:encodes |
gptkb:E2F1_protein
|
| gptkbp:Entrez_Gene_ID |
1869
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
gptkb:transcription_factor
|
| gptkbp:HGNC_ID |
gptkb:HGNC:3113
|
| gptkbp:interactsWith |
gptkb:DP1_protein
gptkb:RB1_protein |
| gptkbp:locatedOnChromosome |
gptkb:20q11.2
|
| gptkbp:memberOf |
gptkb:E2F_family
|
| gptkbp:mutationAssociatedWith |
tumorigenesis
|
| gptkbp:OMIM |
189971
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:E2f1
|
| gptkbp:regulates |
gptkb:G1/S_transition
apoptosis cell differentiation cell proliferation DNA replication cell cycle DNA damage response cell death p53 pathway S phase entry activator E2F binding site |
| gptkbp:UniProtID |
gptkb:Q01094
|
| gptkbp:bfsParent |
gptkb:E2F1
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
E2F1 gene
|