purinergic receptor P2Y, G-protein coupled, 12
GPTKB entity
Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
gptkbp:alternativeName |
P2RY12
P2Y12 |
gptkbp:associatedWith |
hereditary bleeding disorder
|
gptkbp:encodedBy |
gptkb:P2RY12_gene
|
gptkbp:Entrez_Gene_ID |
ENSG00000169313
|
gptkbp:expressedIn |
gptkb:microglia
platelets |
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:function |
gptkb:G_protein-coupled_receptor
platelet aggregation ADP receptor |
gptkbp:HGNC_ID |
15585
|
https://www.w3.org/2000/01/rdf-schema#label |
purinergic receptor P2Y, G-protein coupled, 12
|
gptkbp:inhibitedBy |
gptkb:adenylate_cyclase
|
gptkbp:ligand |
gptkb:ADP
|
gptkbp:locatedIn |
gptkb:cell_membrane
|
gptkbp:locatedOnChromosome |
chromosome 3q25.1
|
gptkbp:memberOf |
purinergic receptor family
G-protein coupled receptor family |
gptkbp:mutationAssociatedWith |
bleeding diathesis
|
gptkbp:OMIM |
609122
|
gptkbp:RefSeq |
NM_022788
|
gptkbp:target |
gptkb:ticagrelor
gptkb:clopidogrel gptkb:prasugrel gptkb:cangrelor |
gptkbp:UniProtID |
Q9H244
|
gptkbp:bfsParent |
gptkb:P2Y12_receptor
|
gptkbp:bfsLayer |
7
|