protein tyrosine phosphatase, non-receptor type 12
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:PTPN12
gptkb:PTP-PEST |
| gptkbp:associatedWith |
gptkb:cancer
cell motility |
| gptkbp:domain |
gptkb:PEST_sequence
PTP domain |
| gptkbp:encodedBy |
PTPN12 gene
|
| gptkbp:Entrez_Gene_ID |
5782
|
| gptkbp:enzymeCommissionNumber |
EC 3.1.3.48
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
dephosphorylation of tyrosine residues
|
| https://www.w3.org/2000/01/rdf-schema#label |
protein tyrosine phosphatase, non-receptor type 12
|
| gptkbp:interactsWith |
gptkb:Grb2
gptkb:PSTPIP1 gptkb:c-Abl p130Cas |
| gptkbp:involvedIn |
cell signaling
regulation of cell differentiation regulation of cell growth regulation of mitotic cycle |
| gptkbp:locatedOnChromosome |
7q11.23
|
| gptkbp:molecularWeight |
88 kDa
|
| gptkbp:OMIM |
176885
|
| gptkbp:regulates |
cell migration
focal adhesion dynamics |
| gptkbp:UniProtID |
gptkb:Q05209
|
| gptkbp:bfsParent |
gptkb:PTPN12
|
| gptkbp:bfsLayer |
7
|