|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD2BP1
CD2 binding protein 1
|
|
gptkbp:associatedWith
|
autoinflammatory syndromes
|
|
gptkbp:discoveredIn
|
1999
|
|
gptkbp:domain
|
SH3 domain
F-BAR domain
|
|
gptkbp:encodedBy
|
PSTPIP1 gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000163681
|
|
gptkbp:expressedIn
|
macrophages
hematopoietic cells
neutrophils
|
|
gptkbp:fullName
|
Proline-serine-threonine phosphatase-interacting protein 1
|
|
gptkbp:function
|
involved in immune response
regulation of actin cytoskeleton
cytoskeletal adaptor protein
|
|
gptkbp:gene
|
gptkb:PSTPIP1
|
|
gptkbp:HGNC_ID
|
HGNC:9560
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PSTPIP1
|
|
gptkbp:interactsWith
|
gptkb:WASp
gptkb:PTPN12
gptkb:CD2AP
|
|
gptkbp:length
|
416 amino acids
|
|
gptkbp:locale
|
gptkb:cell_membrane
gptkb:cytoplasm
|
|
gptkbp:locatedOnChromosome
|
15q24-q25
|
|
gptkbp:molecularWeight
|
47 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:PAPA_syndrome
acne
pyoderma gangrenosum
pyogenic arthritis
|
|
gptkbp:OMIM
|
606347
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
immune system
actin cytoskeleton regulation
|
|
gptkbp:phosphorylates
|
gptkb:tyrosine
serine
threonine
|
|
gptkbp:RefSeq
|
NM_003978
|
|
gptkbp:UniProtID
|
Q9NPB3
|
|
gptkbp:bfsParent
|
gptkb:PSTAP
gptkb:PTPN12
|
|
gptkbp:bfsLayer
|
7
|