PEST sequence

GPTKB entity

Statements (18)
Predicate Object
gptkbp:instanceOf protein sequence motif
gptkbp:associatedWith rapid protein degradation
gptkbp:compatibleWith stable proteins
gptkbp:firstDescribed 1986
Rogers et al.
gptkbp:foundIn proteins
eukaryotic proteins
gptkbp:function signals proteins for degradation by the proteasome
https://www.w3.org/2000/01/rdf-schema#label PEST sequence
gptkbp:namedFor proline, glutamic acid, serine, threonine
gptkbp:recognizedBy ubiquitin-proteasome system
gptkbp:richIn gptkb:glutamic_acid
serine
threonine
proline
gptkbp:usedIn bioinformatics for predicting protein half-life
gptkbp:bfsParent gptkb:PTPN8
gptkbp:bfsLayer 7