primary mediastinal large B-cell lymphoma
GPTKB entity
Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:healthcare_organization
|
| gptkbp:bfsLayer |
3
|
| gptkbp:bfsParent |
gptkb:healthcare_organization
|
| gptkbp:affects |
B-cells
|
| gptkbp:associated_with |
gptkb:HIV
autoimmune diseases |
| gptkbp:can_lead_to |
gptkb:healthcare_organization
respiratory distress thrombosis |
| gptkbp:caused_by |
lymphadenopathy
hepatomegaly splenomegaly |
| https://www.w3.org/2000/01/rdf-schema#label |
primary mediastinal large B-cell lymphoma
|
| gptkbp:is_a |
gptkb:non-Hodgkin_lymphoma
|
| gptkbp:is_associated_with |
B symptoms
|
| gptkbp:is_characterized_by |
C D30 positivity
C D19 positivity BC L2 negativity BC L6 rearrangement MYC rearrangement large B-cells |
| gptkbp:is_considered |
gptkb:aggressive_lymphoma
|
| gptkbp:is_linked_to |
genetic mutations
epigenetic changes chromosomal abnormalities |
| gptkbp:is_often_used_in |
gptkb:Person
young adults females |
| gptkbp:is_part_of |
hematologic malignancies
NHL subtypes |
| gptkbp:is_related_to |
diffuse large B-cell lymphoma
|
| gptkbp:is_studied_in |
clinical trials
|
| gptkbp:is_used_for |
pleural effusion
mediastinal mass superior vena cava syndrome |
| gptkbp:managed_by |
oncologists
hematologists |
| gptkbp:occurs_in |
gptkb:healthcare_organization
other lymphomas |
| gptkbp:origin |
thymus
|
| gptkbp:research_focus |
oncology
hematology |
| gptkbp:social_responsibility |
CT scan
variable imaging studies biopsy PET scan |
| gptkbp:symptoms |
weight loss
cough fever chest pain night sweats |
| gptkbp:treatment |
gptkb:drug
radiation therapy chemotherapy stem cell transplant R-CHOP regimen |