primary mediastinal B-lymphoma

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:disease
leukemia
gptkbp:abbreviation gptkb:PMBCL
gptkbp:differentialDiagnosis gptkb:classical_Hodgkin_lymphoma
thymoma
germ cell tumor
gptkbp:hasGeneticFeature frequent 9p24.1 amplification
gptkbp:hasImmunophenotype CD30 positive
CD20 positive
BCL6 variable
CD10 negative
CD23 positive
MUM1 positive
gptkbp:hasLocation gptkb:mediastinum
gptkbp:hasTypicalAgeOfOnset young adult
gptkbp:hasTypicalSexDistribution female predominance
https://www.w3.org/2000/01/rdf-schema#label primary mediastinal B-lymphoma
gptkbp:ICD-10_code C85.2
gptkbp:originatedIn B-cell
gptkbp:prognosis generally favorable with modern therapy
gptkbp:subclassOf diffuse large B-cell lymphoma
gptkbp:symptom gptkb:superior_vena_cava_syndrome
cough
dyspnea
chest mass
gptkbp:synonym gptkb:primary_mediastinal_large_B-cell_lymphoma
gptkbp:treatment radiation therapy
chemotherapy
immunotherapy
gptkbp:bfsParent gptkb:primary_mediastinal_large_B-cell_lymphoma
gptkbp:bfsLayer 6