primary mediastinal B-cell lymphoma
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
leukemia |
| gptkbp:affects |
gptkb:mediastinum
gptkb:B_cells |
| gptkbp:firstDescribed |
1980s
|
| gptkbp:hasDiagnosticMethod |
biopsy
imaging (CT, PET) |
| gptkbp:hasEpidemiology |
more common in females
typically affects young adults |
| gptkbp:hasGeneticFeature |
JAK2 amplification
PD-L1 overexpression frequent 9p24.1 amplification |
| gptkbp:hasParentDisease |
leukemia
|
| https://www.w3.org/2000/01/rdf-schema#label |
primary mediastinal B-cell lymphoma
|
| gptkbp:ICD-10_code |
C85.2
|
| gptkbp:prognosis |
generally favorable with modern therapy
|
| gptkbp:riskFactor |
female sex
young adult age |
| gptkbp:subclassOf |
diffuse large B-cell lymphoma
|
| gptkbp:symptom |
gptkb:superior_vena_cava_syndrome
cough shortness of breath chest pain |
| gptkbp:synonym |
gptkb:PMBCL
gptkb:primary_mediastinal_large_B-cell_lymphoma |
| gptkbp:treatment |
radiation therapy
chemotherapy immunotherapy |
| gptkbp:bfsParent |
gptkb:primary_mediastinal_large_B-cell_lymphoma
|
| gptkbp:bfsLayer |
6
|