Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
Fc epsilon RII
low affinity immunoglobulin E Fc receptor |
| gptkbp:binds |
gptkb:IgE
|
| gptkbp:discoveredBy |
Stewart Sell
|
| gptkbp:encodedBy |
FCER2 gene
|
| gptkbp:Entrez_Gene_ID |
2208
|
| gptkbp:expressedIn |
gptkb:B_cells
gptkb:follicular_dendritic_cells monocytes some epithelial cells |
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
B cell activation
antigen presentation regulation of IgE levels |
| gptkbp:hasIsoform |
CD23a
CD23b |
| https://www.w3.org/2000/01/rdf-schema#label |
CD23
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19p13.3
|
| gptkbp:molecularWeight |
45 kDa
|
| gptkbp:OMIM |
151445
|
| gptkbp:significance |
involved in allergic diseases
marker for B cell activation target for therapeutic antibodies |
| gptkbp:structure |
type II transmembrane protein
|
| gptkbp:UniProtID |
P06734
|
| gptkbp:bfsParent |
gptkb:small_lymphocytic_lymphoma
gptkb:primary_mediastinal_large_B-cell_lymphoma |
| gptkbp:bfsLayer |
6
|