|
gptkbp:instanceOf
|
gptkb:disease
leukemia
|
|
gptkbp:abbreviation
|
Primary Mediastinal B-cell Lymphoma
|
|
gptkbp:aggression
|
true
|
|
gptkbp:commonChemotherapyRegimen
|
DA-EPOCH-R
R-CHOP
|
|
gptkbp:commonIn
|
young adults
females
|
|
gptkbp:diagnosedBy
|
imaging
biopsy
|
|
gptkbp:differentialDiagnosis
|
gptkb:classical_Hodgkin_lymphoma
thymoma
germ cell tumor
|
|
gptkbp:diseaseCategory
|
leukemia
|
|
gptkbp:distinctFrom
|
gptkb:classical_Hodgkin_lymphoma
|
|
gptkbp:expressedIn
|
gptkb:PD-L2
PD-L1
|
|
gptkbp:firstDescribed
|
1980s
|
|
gptkbp:fullName
|
Primary Mediastinal B-cell Lymphoma
|
|
gptkbp:geneticFeature
|
gptkb:JAK2_mutation
9p24 amplification
|
|
gptkbp:hasNo
|
Epstein-Barr virus association
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PMBCL
|
|
gptkbp:ICD-10_code
|
C85.2
|
|
gptkbp:incidence
|
rare
|
|
gptkbp:location
|
gptkb:mediastinum
|
|
gptkbp:marking
|
gptkb:CD20
gptkb:CD19
gptkb:CD30
gptkb:BCL6
gptkb:CD23
MUM1
|
|
gptkbp:medianAge
|
30-40 years
|
|
gptkbp:originatedIn
|
gptkb:B_cells
|
|
gptkbp:prognosis
|
generally favorable with treatment
|
|
gptkbp:relatedTo
|
diffuse large B-cell lymphoma
|
|
gptkbp:stageName
|
gptkb:Ann_Arbor_staging
|
|
gptkbp:subspecies
|
gptkb:primary_mediastinal_large_B-cell_lymphoma
|
|
gptkbp:symptom
|
gptkb:superior_vena_cava_syndrome
cough
shortness of breath
chest mass
|
|
gptkbp:treatment
|
gptkb:rituximab
gptkb:pembrolizumab
gptkb:nivolumab
radiation therapy
chemotherapy
immunotherapy
|
|
gptkbp:bfsParent
|
gptkb:primary_mediastinal_large_B-cell_lymphoma
|
|
gptkbp:bfsLayer
|
6
|