plasminogen activator inhibitor type 1

URI: https://gptkb.org/entity/plasminogen_activator_inhibitor_type_1
GPTKB entity
Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation gptkb:PAI-1
gptkbp:alternativeName gptkb:serpin_E1
PAI-1 antigen
plasminogen activator inhibitor 1
gptkbp:associatedWith gptkb:cardiovascular_disease
gptkb:metabolic_syndrome
obesity
thrombosis
gptkbp:encodedBy SERPINE1 gene
gptkbp:expressedIn gptkb:thyroid
gptkb:cancer
gptkb:skin
gptkb:pituitary_gland
gptkb:skeletal_muscle
gptkb:adrenal_gland
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
brain
heart
liver
spleen
bone marrow
colon
lymph node
pancreas
vascular smooth muscle cells
lung fibroblasts
gptkbp:foundIn adipose tissue
blood plasma
platelets
endothelial cells
https://www.w3.org/2000/01/rdf-schema#label plasminogen activator inhibitor type 1
gptkbp:inhibitedBy gptkb:tissue_plasminogen_activator
gptkb:urokinase
gptkbp:locatedOnChromosome 7q22.1
gptkbp:memberOf serpin family
gptkbp:molecularWeight 45 kDa
gptkbp:OMIM 173360
gptkbp:PDB 1B3K
gptkbp:regulates fibrinolysis
plasminogen activation
gptkbp:UniProtID gptkb:P05121
gptkbp:bfsParent gptkb:PAI-1
gptkb:SERPINE1
gptkbp:bfsLayer 7