Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:PAI-1
gptkb:plasminogen_activator_inhibitor-1 |
| gptkbp:associatedWith |
gptkb:cardiovascular_disease
gptkb:metabolic_syndrome thrombosis |
| gptkbp:decreasedIn |
physical activity
weight loss |
| gptkbp:encodedBy |
SERPINE1 gene
|
| gptkbp:expressedIn |
liver
adipose tissue platelets endothelial cells |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
inhibits tissue plasminogen activator
inhibits urokinase |
| https://www.w3.org/2000/01/rdf-schema#label |
serpin E1
|
| gptkbp:improves |
obesity
inflammation insulin resistance |
| gptkbp:inhibitedBy |
serine proteases
|
| gptkbp:location |
chromosome 7q22.1
|
| gptkbp:medicalUse |
biomarker for cardiovascular risk
|
| gptkbp:molecularWeight |
45 kDa
|
| gptkbp:OMIM |
173360
|
| gptkbp:PDB |
1B3K
|
| gptkbp:regulates |
fibrinolysis
extracellular matrix remodeling |
| gptkbp:structure |
serpin superfamily
|
| gptkbp:UniProtID |
gptkb:P05121
|
| gptkbp:bfsParent |
gptkb:SERPINE1
|
| gptkbp:bfsLayer |
7
|