|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Calgranulin-A
gptkb:Migration_inhibitory_factor-related_protein_8
MRP8
|
|
gptkbp:associatedWith
|
inflammatory diseases
psoriasis
rheumatoid arthritis
cystic fibrosis
|
|
gptkbp:encodedBy
|
S100A8 gene
|
|
gptkbp:Entrez_Gene_ID
|
6279
ENSG00000143546
|
|
gptkbp:expressedIn
|
monocytes
neutrophils
|
|
gptkbp:firstDescribed
|
1989
|
|
gptkbp:formsComplexWith
|
gptkb:S100A9
|
|
gptkbp:function
|
calcium-binding protein
involved in inflammatory processes
|
|
gptkbp:hasCalciumBindingSite
|
yes
|
|
gptkbp:hasMetalBindingSite
|
copper
zinc
|
|
gptkbp:HGNC_ID
|
10498
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P05121
|
|
gptkbp:involvedIn
|
immune response
leukocyte migration
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q21
|
|
gptkbp:location
|
gptkb:cytoplasm
secreted
|
|
gptkbp:molecularWeight
|
10.8 kDa
|
|
gptkbp:OMIM
|
123840
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:partOf
|
gptkb:S100_protein_family
|
|
gptkbp:PDB
|
1MR8
1XK4
4GGF
|
|
gptkbp:postTranslationalModification
|
phosphorylation
oxidation
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:sequence
|
93 amino acids
|
|
gptkbp:structure
|
gptkb:EF-hand_domain
|
|
gptkbp:UniProt_entry_name
|
gptkb:Protein_S100-A8
|
|
gptkbp:UniProtID
|
gptkb:P05121
|
|
gptkbp:bfsParent
|
gptkb:PAI-1
gptkb:SERPINE1
|
|
gptkbp:bfsLayer
|
7
|