phosphoinositide 3-kinase alpha complex
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
PI3Kα
phosphatidylinositol 3-kinase alpha complex |
| gptkbp:catalyzes |
phosphorylation of phosphatidylinositol-4,5-bisphosphate
|
| gptkbp:encodedBy |
gptkb:PIK3CA_gene
PIK3R1 gene |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:has_catalytic_subunit |
gptkb:p110α
|
| gptkbp:has_regulatory_subunit |
gptkb:p85α
|
| https://www.w3.org/2000/01/rdf-schema#label |
phosphoinositide 3-kinase alpha complex
|
| gptkbp:involves |
gptkb:PI3K/AKT_signaling_pathway
gptkb:cancer cell proliferation cell survival metabolism cell growth |
| gptkbp:produces |
phosphatidylinositol-3,4,5-trisphosphate
|
| gptkbp:subunit |
gptkb:PIK3R1
gptkb:PIK3R2 gptkb:PIK3R3 gptkb:PIK3CA |
| gptkbp:target |
gptkb:alpelisib
gptkb:BYL719 |
| gptkbp:UniProtID |
P27986 (p85α)
P42336 (p110α) |
| gptkbp:bfsParent |
gptkb:catalytic_subunit_of_PI3K_alpha
|
| gptkbp:bfsLayer |
6
|