Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
PI3K regulatory subunit alpha
phosphoinositide-3-kinase regulatory subunit alpha |
| gptkbp:component |
gptkb:phosphoinositide_3-kinase_(PI3K)
|
| gptkbp:encodedBy |
PIK3R1 gene
|
| gptkbp:function |
binds to phosphorylated tyrosine residues
regulates PI3K catalytic activity |
| https://www.w3.org/2000/01/rdf-schema#label |
p85α
|
| gptkbp:interactsWith |
gptkb:p110α
gptkb:p110δ gptkb:p110β |
| gptkbp:involvedIn |
cell survival
cell signaling cell growth regulation insulin signaling pathway |
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:mutationAssociatedWith |
gptkb:cancer
insulin resistance |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:bfsParent |
gptkb:Class_IA_PI3K
gptkb:PIK3R1 |
| gptkbp:bfsLayer |
6
|