catalytic subunit of PI3K alpha
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:PIK3CA
|
| gptkbp:biologicalProcess |
kinase activity
|
| gptkbp:component |
gptkb:phosphoinositide_3-kinase_alpha_complex
|
| gptkbp:encodedBy |
gptkb:PIK3CA_gene
|
| gptkbp:enzymeCommissionNumber |
2.7.1.153
|
| gptkbp:function |
catalyzes phosphorylation of phosphatidylinositol-4,5-bisphosphate
involved in cell growth, proliferation, differentiation, motility, survival |
| gptkbp:gene |
gptkb:PIK3CA
|
| https://www.w3.org/2000/01/rdf-schema#label |
catalytic subunit of PI3K alpha
|
| gptkbp:interactsWith |
regulatory subunit p85
|
| gptkbp:length |
1068 amino acids
|
| gptkbp:locatedOnChromosome |
3q26.32
|
| gptkbp:molecularWeight |
124 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:endometrial_cancer colorectal cancer |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
gptkb:PI3K-Akt_signaling_pathway
|
| gptkbp:UniProtID |
gptkb:P42336
|
| gptkbp:bfsParent |
gptkb:PIK3CA
|
| gptkbp:bfsLayer |
5
|