Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:ERK1/2
gptkb:MAPK_pathway |
| gptkbp:alternativeName |
gptkb:RSK1
RPS6KA1 |
| gptkbp:encodedBy |
RPS6KA1 gene
|
| gptkbp:fullName |
ribosomal S6 kinase
|
| gptkbp:function |
regulation of cell proliferation
regulation of cell survival regulation of cell growth serine/threonine kinase activity phosphorylation of transcription factors |
| https://www.w3.org/2000/01/rdf-schema#label |
p90RSK
|
| gptkbp:inhibitedBy |
BI-D1870
SL0101 |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
chromosome 1p36.1
|
| gptkbp:molecularWeight |
90 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
gptkb:CREB
gptkb:BAD gptkb:GSK3 gptkb:c-Fos NFAT3 |
| gptkbp:proteinFamily |
RSK family
|
| gptkbp:role |
gptkb:cancer
gptkb:cardiovascular_disease neurological disorders |
| gptkbp:structure |
contains two kinase domains
|
| gptkbp:UniProtID |
Q15418
|
| gptkbp:bfsParent |
gptkb:p44_MAPK
|
| gptkbp:bfsLayer |
7
|