Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:phosphatidylinositol-4,5-bisphosphate_3-kinase_catalytic_subunit_beta_isoform
|
| gptkbp:component |
gptkb:phosphoinositide_3-kinase_(PI3K)_complex
|
| gptkbp:encodedBy |
gptkb:PIK3CB_gene
|
| gptkbp:function |
catalytic subunit of class IA PI3K
|
| https://www.w3.org/2000/01/rdf-schema#label |
p110β
|
| gptkbp:interactsWith |
p85 regulatory subunit
|
| gptkbp:involvedIn |
cell proliferation
cell survival cancer progression cell growth insulin signaling pathway |
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:molecularWeight |
110 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:phosphorylates |
gptkb:phosphatidylinositol_(4,5)-bisphosphate_(PIP2)
|
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:target |
PI3K inhibitors
|
| gptkbp:UniProtID |
gptkb:P42338
|
| gptkbp:bfsParent |
gptkb:Class_IA_PI3K
gptkb:PIK3CB_(p110β) |
| gptkbp:bfsLayer |
6
|