|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
environmental stress
pro-inflammatory cytokines
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:encodedBy
|
gptkb:MAPK12_gene
gptkb:MAPK13_gene
gptkb:MAPK14_gene
gptkb:MAPK11_gene
|
|
gptkbp:function
|
signal transduction
inflammatory response
cellular response to stress
|
|
gptkbp:GO_term
|
GO:0000165
|
|
gptkbp:hasIsoform
|
gptkb:p38α
gptkb:p38β
gptkb:p38γ
gptkb:p38δ
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
p38 MAP kinase family
|
|
gptkbp:inhibitedBy
|
gptkb:SB203580
gptkb:BIRB_796
|
|
gptkbp:involvedIn
|
cell proliferation
inflammation
immune response
cell death
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:member
|
gptkb:MAPK11
gptkb:MAPK12
gptkb:MAPK13
gptkb:MAPK14
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
stress-activated protein kinase pathway
|
|
gptkbp:phosphorylates
|
transcription factors
cytoskeletal proteins
protein kinases
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell cycle
cytokine production
|
|
gptkbp:relatedTo
|
gptkb:ERK_pathway
gptkb:JNK_pathway
|
|
gptkbp:subclassOf
|
gptkb:MAP_kinase_family
|
|
gptkbp:UniProtID
|
gptkb:P53779
gptkb:Q15759
O15264
P53778
|
|
gptkbp:bfsParent
|
gptkb:p38_beta
gptkb:p38_delta
gptkb:p38_gamma
|
|
gptkbp:bfsLayer
|
7
|