|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:PRKM11
gptkb:SAPK2b
gptkb:p38beta
|
|
gptkbp:alternativeName
|
gptkb:p38_beta
gptkb:PRKM11
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodes
|
gptkb:Mitogen-activated_protein_kinase_11
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000185386
5600
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
signal transduction
inflammatory response
cellular response to stress
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0004672 (protein kinase activity)
GO:0005524 (ATP binding)
GO:0000165 (MAPK cascade)
|
|
gptkbp:hasTranscriptVariant
|
MAPK11-201
MAPK11-202
MAPK11-203
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6871
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK11 gene
|
|
gptkbp:involvedIn
|
cell proliferation
immune response
response to cytokines
response to environmental stress
|
|
gptkbp:length
|
364 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 22
|
|
gptkbp:memberOf
|
gptkb:MAP_kinase_family
|
|
gptkbp:molecularWeight
|
41 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
inflammatory diseases
|
|
gptkbp:OMIM
|
602399
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Mapk11
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
stress-activated protein kinase signaling cascade
|
|
gptkbp:phosphorylates
|
Thr180
Tyr182
|
|
gptkbp:product
|
MAP kinase p38 beta
|
|
gptkbp:RefSeq
|
gptkb:NM_002751
|
|
gptkbp:regulates
|
apoptosis
differentiation
transcription factors
cell cycle
|
|
gptkbp:UniProtID
|
gptkb:Q15759
|
|
gptkbp:bfsParent
|
gptkb:p38_beta
|
|
gptkbp:bfsLayer
|
7
|