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gptkbp:instanceOf
|
gptkb:cancer
gptkb:disease
Small Cell Lung Cancer
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|
gptkbp:affectsOrgan
|
gptkb:cancer
|
|
gptkbp:characteristic
|
rapid growth
early metastasis
highly malignant
|
|
gptkbp:hasDiagnosticMethod
|
imaging
biopsy
|
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gptkbp:hasImmunohistochemistryMarker
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gptkb:CD56
gptkb:TTF-1
chromogranin
synaptophysin
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gptkbp:hasMedianSurvival
|
16-24 months (limited stage)
8-13 months (extensive stage)
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gptkbp:hasMicroscopicFeature
|
small round blue cells
scant cytoplasm
high mitotic rate
nuclear molding
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gptkbp:hasParaneoplasticSyndrome
|
gptkb:Lambert-Eaton_myasthenic_syndrome
gptkb:Cushing_syndrome
gptkb:SIADH
|
|
gptkbp:hasType
|
neuroendocrine cell
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
oat cell carcinoma
|
|
gptkbp:ICD-10_code
|
C34
|
|
gptkbp:incidence
|
about 15% of lung cancers
|
|
gptkbp:location
|
central lung
|
|
gptkbp:mutationAssociatedWith
|
gptkb:RB1
gptkb:TP53
|
|
gptkbp:OMIM
|
613043
|
|
gptkbp:prognosis
|
poor
|
|
gptkbp:riskFactor
|
smoking
|
|
gptkbp:stageName
|
extensive stage
limited stage
|
|
gptkbp:subspecies
|
gptkb:cancer
|
|
gptkbp:symptom
|
weight loss
cough
chest pain
hemoptysis
dyspnea
|
|
gptkbp:synonym
|
gptkb:small_cell_lung_carcinoma
small cell carcinoma
|
|
gptkbp:treatment
|
radiation therapy
chemotherapy
immunotherapy
surgery (rarely)
|
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gptkbp:bfsParent
|
gptkb:small_cell_lung_carcinoma
|
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gptkbp:bfsLayer
|
7
|