Lambert-Eaton myasthenic syndrome

GPTKB entity

Predicate	Object
gptkbp:instanceOf	autoimmune disease muscular dystrophy
gptkbp:abbreviation	gptkb:LEMS
gptkbp:affects	neuromuscular junction
gptkbp:associatedWith	Small Cell Lung Cancer
gptkbp:autoantibodyTarget	P/Q-type voltage-gated calcium channels
gptkbp:causedBy	autoantibodies against voltage-gated calcium channels
gptkbp:diagnosedBy	electromyography antibody testing
gptkbp:differentialDiagnosis	gptkb:myasthenia_gravis
gptkbp:firstDescribed	1956
https://www.w3.org/2000/01/rdf-schema#label	Lambert-Eaton myasthenic syndrome
gptkbp:ICD-10_code	gptkb:G70.3
gptkbp:namedAfter	gptkb:Lee_Eaton gptkb:Edward_Lambert
gptkbp:onset	adulthood
gptkbp:prevalence	rare
gptkbp:symptom	muscle weakness autonomic dysfunction dry mouth difficulty walking reduced tendon reflexes
gptkbp:treatment	gptkb:3,4-diaminopyridine gptkb:pyridostigmine immunosuppressants
gptkbp:bfsParent	gptkb:3,4-diaminopyridine gptkb:LEMS gptkb:small_cell_lung_carcinoma gptkb:paraneoplastic_syndromes gptkb:Small_cell_lung_cancer
gptkbp:bfsLayer	7