Cushing syndrome

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects adults
children
humans
gptkbp:alsoKnownAs hypercortisolism
gptkbp:category endocrine disease
hormonal disorder
gptkbp:causedBy excess cortisol
gptkbp:complication gptkb:cardiovascular_disease
gptkb:bone
gptkb:diabetes_mellitus
infections
gptkbp:diagnosedBy gptkb:dexamethasone_suppression_test
24-hour urinary free cortisol
late-night salivary cortisol
serum ACTH measurement
gptkbp:differentialDiagnosis gptkb:depression
gptkb:polycystic_ovary_syndrome
gptkb:metabolic_syndrome
obesity
gptkbp:firstDescribed gptkb:Harvey_Cushing
https://www.w3.org/2000/01/rdf-schema#label Cushing syndrome
gptkbp:ICD-10_code E24
gptkbp:MeSH_ID D003480
gptkbp:namedAfter gptkb:Harvey_Cushing
gptkbp:prevalence rare
gptkbp:riskFactor adrenal tumor
pituitary adenoma
ectopic ACTH production
long-term corticosteroid use
gptkbp:symptom gptkb:depression
gptkb:bone
gptkb:diabetes_mellitus
hypertension
muscle weakness
poor wound healing
acne
weight gain
easy bruising
hirsutism
moon face
purple striae
buffalo hump
gptkbp:treatment surgery
radiation therapy
medications
discontinuation of corticosteroids
gptkbp:bfsParent gptkb:ectopic_ACTH_syndrome
gptkb:small_cell_lung_carcinoma
gptkb:paraneoplastic_syndromes
gptkb:Carney_complex
gptkb:PDE11
gptkb:Small_cell_lung_cancer
gptkbp:bfsLayer 7