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gptkbp:instanceOf
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syndrome
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gptkbp:abbreviation
|
gptkb:Syndrome_of_Inappropriate_Antidiuretic_Hormone_Secretion
|
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gptkbp:associatedWith
|
gptkb:cyclophosphamide
gptkb:pneumonia
gptkb:paraneoplastic_syndromes
gptkb:SSRIs
gptkb:carbamazepine
meningitis
stroke
tuberculosis
head trauma
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gptkbp:cause
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hyponatremia
|
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gptkbp:causedBy
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gptkb:small_cell_lung_carcinoma
certain medications
pulmonary diseases
central nervous system disorders
|
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gptkbp:characterizedBy
|
euvolemic hyponatremia
inappropriately concentrated urine
low plasma osmolality
|
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gptkbp:complication
|
seizures
cerebral edema
death (if untreated)
|
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gptkbp:diagnosedBy
|
high urine osmolality
high urine sodium
low serum osmolality
low serum sodium
|
|
gptkbp:differentialDiagnosis
|
hypothyroidism
adrenal insufficiency
diuretic use
|
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gptkbp:firstDescribed
|
1957
|
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gptkbp:fullName
|
gptkb:Syndrome_of_Inappropriate_Antidiuretic_Hormone_Secretion
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SIADH
|
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gptkbp:labFinding
|
BUN low
serum uric acid low
urine osmolality > 100 mOsm/kg
urine sodium > 40 mmol/L
|
|
gptkbp:mechanismOfAction
|
excess ADH secretion
increased water reabsorption in kidneys
|
|
gptkbp:namedFor
|
gptkb:Frederic_Bartter
gptkb:William_Schwartz
|
|
gptkbp:symptom
|
confusion
nausea
headache
coma
seizures
|
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gptkbp:treatment
|
gptkb:demeclocycline
gptkb:vasopressin_receptor_antagonists
fluid restriction
|
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gptkbp:bfsParent
|
gptkb:Small_Cell_Lung_Cancer
|
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gptkbp:bfsLayer
|
5
|