|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:NKX2-1
|
|
gptkbp:category
|
homeobox protein
nuclear protein
|
|
gptkbp:diagnosedBy
|
gptkb:lung_adenocarcinoma
gptkb:small_cell_lung_carcinoma
thyroid carcinoma
|
|
gptkbp:encodedBy
|
NKX2-1 gene
|
|
gptkbp:Entrez_Gene_ID
|
7080
|
|
gptkbp:expressedIn
|
thyroid gland
brain tissue
lung tissue
|
|
gptkbp:foundIn
|
humans
|
|
gptkbp:fullName
|
Thyroid Transcription Factor-1
|
|
gptkbp:function
|
transcription factor
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TTF-1
|
|
gptkbp:importantFor
|
development of forebrain
development of lung
development of thyroid
|
|
gptkbp:locatedOnChromosome
|
chromosome 14q13.3
|
|
gptkbp:mutationAssociatedWith
|
gptkb:benign_hereditary_chorea
respiratory distress
hypothyroidism
|
|
gptkbp:negativeIn
|
gptkb:colorectal_carcinoma
squamous cell carcinoma of the lung
|
|
gptkbp:regulates
|
expression of brain-specific genes
expression of lung-specific genes
expression of thyroid-specific genes
|
|
gptkbp:UniProtID
|
P43699
|
|
gptkbp:usedAsMarkerIn
|
immunohistochemistry
|
|
gptkbp:bfsParent
|
gptkb:lung_adenocarcinoma
|
|
gptkbp:bfsLayer
|
6
|