Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:NCT
|
| gptkbp:associatedWith |
familial acne inversa
|
| gptkbp:component |
gptkb:gamma-secretase_complex
|
| gptkbp:discoveredBy |
1999
|
| gptkbp:function |
regulates proteolytic activity of gamma-secretase
|
| gptkbp:gene |
NCSTN
|
| https://www.w3.org/2000/01/rdf-schema#label |
nicastrin
|
| gptkbp:interactsWith |
gptkb:presenilin-1
gptkb:APH-1 gptkb:PEN-2 |
| gptkbp:involves |
gptkb:Alzheimer's_disease
gptkb:Notch_signaling_pathway |
| gptkbp:locatedOnChromosome |
chromosome 1q23.2
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:molecularWeight |
~75 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:subunit |
gptkb:gamma-secretase
|
| gptkbp:UniProtID |
Q92542
|
| gptkbp:bfsParent |
gptkb:APP_(amyloid_precursor_protein)
gptkb:presenilin-1 gptkb:Amyloid_precursor_protein gptkb:gamma-secretase gptkb:amyloid_precursor_protein |
| gptkbp:bfsLayer |
8
|