neurotrophic receptor tyrosine kinase 1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:gene
gptkbp:alsoKnownAs	gptkb:TrkA gptkb:NTRK1
gptkbp:discoveredBy	Lamballe et al.
gptkbp:discoveredIn	1991
gptkbp:domain	transmembrane domain extracellular ligand-binding domain intracellular tyrosine kinase domain
gptkbp:encodedBy	gptkb:NTRK1_gene
gptkbp:Entrez_Gene_ID	4914 ENSG00000198400
gptkbp:expressedIn	gptkb:nervous_system
gptkbp:function	tyrosine kinase activity receptor for nerve growth factor (NGF)
gptkbp:HGNC_ID	8031
gptkbp:involvedIn	neuronal differentiation neuronal survival
gptkbp:ligand	gptkb:nerve_growth_factor_(NGF)
gptkbp:locatedOnChromosome	chromosome 1
gptkbp:memberOf	neurotrophic tyrosine receptor kinase family
gptkbp:mutationAssociatedWith	gptkb:cancer gptkb:congenital_insensitivity_to_pain_with_anhidrosis
gptkbp:OMIM	191315
gptkbp:orthologInMouse	gptkb:Ntrk1
gptkbp:target	gptkb:entrectinib gptkb:larotrectinib
gptkbp:UniProtID	gptkb:P04629
gptkbp:bfsParent	gptkb:NTRK1 gptkb:NTRK1_gene gptkb:HGNC:8007
gptkbp:bfsLayer	7
http://www.w3.org/2000/01/rdf-schema#label	neurotrophic receptor tyrosine kinase 1