|
gptkbp:instanceOf
|
gptkb:vitamin_A
quinone
|
|
gptkbp:affiliatedWith
|
gptkb:vitamin_K_group
|
|
gptkbp:approvedBy
|
dietary supplement
|
|
gptkbp:biosynthesized_from
|
gut microbiota
|
|
gptkbp:CASNumber
|
gptkb:11032-49-8_(MK-4)
2124-57-4 (MK-7)
|
|
gptkbp:chemicalFormula
|
C11H8O2 (core structure)
|
|
gptkbp:color
|
yellow crystals
|
|
gptkbp:contraindication
|
gptkb:warfarin
|
|
gptkbp:deficiencyCauses
|
bleeding disorders
|
|
gptkbp:discoveredBy
|
Edward Doisy
|
|
gptkbp:excretion
|
urine
bile
|
|
gptkbp:foundIn
|
gptkb:meat
gptkb:cheese
gptkb:Bacteria
gptkb:natto
eggs
dairy products
sauerkraut
animal products
fermented foods
|
|
gptkbp:halfLife
|
1–3 days (MK-7)
hours (MK-4)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
menaquinones (K2)
|
|
gptkbp:IUPACName
|
gptkb:2-methyl-3-polyprenyl-1,4-naphthoquinone
|
|
gptkbp:meltingPoint
|
53–54 °C (MK-4)
53–54 °C (MK-7)
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
444.65 g/mol (MK-4)
649.0 g/mol (MK-7)
|
|
gptkbp:producedBy
|
gptkb:Bacteria
gptkb:Bacillus_subtilis
gptkb:Lactococcus_lactis
|
|
gptkbp:regulates
|
gptkb:European_Food_Safety_Authority
gptkb:U.S._Food_and_Drug_Administration
|
|
gptkbp:relatedTo
|
gptkb:phylloquinone_(K1)
|
|
gptkbp:role
|
gamma-carboxylation of glutamic acid residues
|
|
gptkbp:sideEffect
|
hypercoagulation (rare)
|
|
gptkbp:solubility
|
fat-soluble
|
|
gptkbp:subspecies
|
gptkb:MK-4
gptkb:MK-7
gptkb:MK-8
gptkb:MK-9
|
|
gptkbp:usedFor
|
bone health
cardiovascular health
blood clotting
|
|
gptkbp:usedIn
|
treatment of osteoporosis
treatment of vitamin K deficiency
|
|
gptkbp:bfsParent
|
gptkb:Vitamin_K
|
|
gptkbp:bfsLayer
|
5
|