macrophage migration inhibitory factor

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein cytokine
gptkbp:alternativeName	gptkb:GIF gptkb:MIF glycosylation-inhibiting factor
gptkbp:associatedWith	gptkb:cancer asthma sepsis rheumatoid arthritis
gptkbp:biologicalProcess	cytokine activity tautomerase activity
gptkbp:discoveredBy	gptkb:John_David
gptkbp:discoveredIn	1966
gptkbp:Entrez_Gene_ID	ENSG00000240972 GC01M002409
gptkbp:expressedIn	gptkb:pituitary_gland gptkb:T_cells macrophages
gptkbp:foundIn	gptkb:Mus_musculus gptkb:Homo_sapiens
gptkbp:function	regulation of immune response inhibition of macrophage migration pro-inflammatory mediator
gptkbp:gene	gptkb:MIF
gptkbp:HGNC_ID	7097
https://www.w3.org/2000/01/rdf-schema#label	macrophage migration inhibitory factor
gptkbp:involves	immune response inflammatory response
gptkbp:length	115
gptkbp:locatedOnChromosome	22q11.23
gptkbp:molecularWeight	12.5 kDa
gptkbp:OMIM	153620
gptkbp:orthologInMouse	gptkb:Mif
gptkbp:PDB	1MFI
gptkbp:recipient	gptkb:CD74 gptkb:CXCR2 gptkb:CXCR4 gptkb:CXCR7
gptkbp:RefSeq	NM_002415
gptkbp:regulates	apoptosis cell proliferation angiogenesis oxidative stress response glucocorticoid action
gptkbp:structure	homotrimer
gptkbp:UniProtID	P14174
gptkbp:bfsParent	gptkb:MIF_gene gptkb:Mif gptkb:phenylpyruvate_tautomerase
gptkbp:bfsLayer	8