Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:activatedBy |
gptkb:MAPK_pathway
gptkb:PI3K-Akt_pathway JAK2-STAT3 pathway |
| gptkbp:dysregulationAssociatedWith |
gptkb:type_2_diabetes
gptkb:metabolic_syndrome obesity leptin resistance |
| gptkbp:GO_term |
GO:0033210
|
| https://www.w3.org/2000/01/rdf-schema#label |
leptin signaling pathway
|
| gptkbp:inhibitedBy |
gptkb:SOCS3
|
| gptkbp:involves |
gptkb:JAK2
gptkb:MAPK gptkb:SOCS3 gptkb:PI3K gptkb:leptin gptkb:STAT3 leptin receptor (LEPR) |
| gptkbp:KEGGID |
hsa04920
|
| gptkbp:launched |
leptin binding to LEPR
|
| gptkbp:occurredIn |
hypothalamus
|
| gptkbp:regulates |
metabolism
appetite body weight energy homeostasis |
| gptkbp:bfsParent |
gptkb:PTPN1
|
| gptkbp:bfsLayer |
7
|