Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cytokine |
| gptkbp:alternativeName |
gptkb:interleukin-6
gptkb:IL-6 |
| gptkbp:discoveredBy |
Tada Taniguchi
|
| gptkbp:discoveredIn |
1986
|
| gptkbp:encodedBy |
gptkb:IL6_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
immune response regulation
inflammation mediation |
| https://www.w3.org/2000/01/rdf-schema#label |
interferon beta-2
|
| gptkbp:locatedOnChromosome |
7p15.3
|
| gptkbp:molecularWeight |
21 kDa
|
| gptkbp:OMIM |
147620
|
| gptkbp:PDB |
gptkb:1ALU
|
| gptkbp:promotion |
B cell differentiation
antibody production acute phase response |
| gptkbp:recipient |
gptkb:IL-6_receptor
|
| gptkbp:role |
gptkb:cancer
autoimmune diseases rheumatoid arthritis chronic inflammation COVID-19 severity |
| gptkbp:secretes |
gptkb:T_cells
macrophages |
| gptkbp:UniProtID |
gptkb:P05231
|
| gptkbp:bfsParent |
gptkb:interleukin-6
gptkb:human_interleukin-6 |
| gptkbp:bfsLayer |
6
|