IL-6 receptor

GPTKB entity

Statements (61)
Predicate Object
gptkbp:instance_of gptkb:protein
gptkbp:bfsLayer 5
gptkbp:bfsParent gptkb:Actemra
gptkbp:associated_with inflammation
gptkbp:function binds interleukin-6
gptkbp:has_role cytokine signaling
https://www.w3.org/2000/01/rdf-schema#label IL-6 receptor
gptkbp:interacts_with gp130
gptkbp:is_involved_in gptkb:asthma
gptkb:healthcare_organization
gptkb:Crohn's_disease
gptkb:systemic_lupus_erythematosus
gptkb:Company
gptkb:psychologist
gptkb:rheumatoid_arthritis
apoptosis
cell differentiation
cell proliferation
cellular homeostasis
cellular metabolism
cellular stress response
immune response
protein synthesis
signal transduction
allergic reactions
chronic diseases
metabolic syndrome
obesity
neuroinflammation
stress response
fibrosis
cardiovascular diseases
fungal infections
sepsis
extracellular matrix remodeling
immune tolerance
psoriasis
cancer progression
angiogenesis
gene expression regulation
immune cell activation
tissue repair
viral infections
cell migration
hormonal regulation
bacterial infections
neuroendocrine signaling
cellular communication
cytokine production
chronic obstructive pulmonary disease
pain signaling
metabolic regulation
COVID-19 complications
joint diseases
chemokine signaling
gptkbp:is_linked_to autoimmune disorders
gptkbp:is_represented_in gptkb:T_cells
B cells
monocytes
gptkbp:located_in cell membrane
gptkbp:targets therapeutic antibodies