integrin beta 1 (ITGB1)

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName CD29
fibronectin receptor beta subunit
gptkbp:biologicalProcess embryonic development
wound healing
cell migration
extracellular matrix organization
integrin binding
extracellular matrix binding
gptkbp:cellularComponent gptkb:plasma_membrane
focal adhesion
gptkbp:Entrez_Gene_ID 3688
gptkbp:expressedIn many tissues
gptkbp:formsComplexWith integrin alpha subunits
gptkbp:formsHeterodimerWith gptkb:integrin_alpha_1
integrin alpha 2
integrin alpha 3
integrin alpha 4
integrin alpha 5
integrin alpha 6
integrin alpha 7
integrin alpha 8
gptkbp:function signal transduction
cell adhesion
gptkbp:gene gptkb:ITGB1
gptkbp:HGNC_ID 6153
https://www.w3.org/2000/01/rdf-schema#label integrin beta 1 (ITGB1)
gptkbp:interactsWith gptkb:fibronectin
gptkb:talin
gptkb:filamin
gptkb:laminin
collagen
focal adhesion kinase (FAK)
tenascin
kindlin
ICAP1
gptkbp:involved_in_disease gptkb:cancer
muscular dystrophy
fibrosis
gptkbp:length 798
gptkbp:locatedOnChromosome gptkb:10q22.1
gptkbp:molecularWeight 88 kDa
gptkbp:OMIM 135630
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 3VI3
gptkbp:postTranslationalModification phosphorylation
glycosylation
gptkbp:UniProtID P05556
gptkbp:bfsParent gptkb:ITG2
gptkbp:bfsLayer 7