Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:cytokine
|
| gptkbp:alsoKnownAs |
gptkb:CXCL8
gptkb:IL-8 |
| gptkbp:category |
gptkb:cytokine
|
| gptkbp:discoveredIn |
1987
|
| gptkbp:encodedBy |
gptkb:CXCL8_gene
|
| gptkbp:function |
chemotaxis of neutrophils
inflammatory response mediator |
| gptkbp:inhibitedBy |
gptkb:glucocorticoids
|
| gptkbp:length |
99 amino acids (precursor)
72 amino acids (mature form) |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4q13-q21
|
| gptkbp:molecularWeight |
8 kDa
|
| gptkbp:PDB |
1IL8
|
| gptkbp:promotion |
gptkb:IL-1
gptkb:TNF-alpha bacterial products |
| gptkbp:recipient |
gptkb:CXCR2
gptkb:CXCR1 |
| gptkbp:role |
asthma
cancer progression inflammatory diseases chronic obstructive pulmonary disease |
| gptkbp:secretes |
macrophages
endothelial cells epithelial cells |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
monomer or homodimer
|
| gptkbp:UniProtID |
P10145
|
| gptkbp:bfsParent |
gptkb:Cytokine-induced_neutrophil_chemoattractant
|
| gptkbp:bfsLayer |
7
|
| http://www.w3.org/2000/01/rdf-schema#label |
human interleukin-8
|